Prostate cancer-specific survival following salvage radiotherapy vs observation in men with biochemical recurrence after radical prostatectomy.

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EAU guidelines on prostate cancer. Part II: Treatment of advanced, relapsing, and castration-resistant prostate cancer. (2011, background): “Even inmenwith PSA DT 6mo, salvage RT was reported to improve PCa-specific survival if given within 2 yr following a rise in the PSA level [52].”
EAU-ESTRO-SIOG Guidelines on Prostate Cancer. Part II: Treatment of Relapsing, Metastatic, and Castration-Resistant Prostate Cancer. (2017, methodology): “soft tissue lesion using the Response Evaluation Criteria in Solid Tumours [8,25]”
EAU-EANM-ESTRO-ESUR-SIOG Guidelines on Prostate Cancer. Part II-2020 Update: Treatment of Relapsing and Metastatic Prostate Cancer. (2020, background): “The risk of subsequent metastases, and PCa-specific and overall mortality may be predicted by the initial clinical and pathological factors (eg, T category, PSA, International Society of Urological Pathology [ISUP] grade) and PSA kinetics (PSA doubling time [PSA-DT] and interval to PSA failure) [6].”
Single-Molecule enzyme-linked immunosorbent assay detects serum proteins at subfemtomolar concentrations (2010, background): “The ability to accurately quantify PSA levels in patients who have undergone prostatectomy at very low concentrations (”