Determinants of enhancer and promoter activities of regulatory elements

By R. Andersson, Albin Sandelin. Nature reviews genetics, 2019

597 citations recorded by the source corpus.

Subfields: Molecular Biology

View Paper: https://www.semanticscholar.org/paper/63590348b55db90b3be732e759d2feb9d105bd05

Citations in the corpus

• CADD v1.7: using protein language models, regulatory CNNs and other nucleotide-level scores to improve genome-wide variant predictions (2024, unknown): “From these and other modeling efforts, open-chromatin information like DNase-seq or A T AC-seq seem to provide good approximations for predicting regulatory variant effects, for example the activity measured from massively parallel reporter assays (MPRAs) ( 48–51 ).”