MicroRNA-146A contributes to abnormal activation of the type I interferon pathway in human lupus by targeting the key signaling proteins.

By Yuanjia Tang, Xiaobing Luo, H. Cui, X. Ni, Min Yuan, Yanzhi Guo, Xin-fang Huang, Haibo Zhou, N. de Vries, P. Tak and 2 more. Arthritis & Rheumatism, 2009

768 citations recorded by the source corpus.

Subfields: Cancer Research, Immunology, Rheumatology

View Paper: https://www.semanticscholar.org/paper/6355b496e622c68d309ece77e6883129a05d23f6

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Cancer Research

1. David Baltimore
2. M. Boldin
3. Alexander Y. Rudensky
4. K. Taganov
5. Ryan M. O’Connell
6. D. Rao
7. C. Harris
8. Aadel A Chaudhuri

In Immunology

1. Li-Fan Lu
2. David Baltimore
3. A. Chaudhry
4. Alexander Y. Rudensky
5. A. Yoshimura
6. M. Boldin
7. K. Taganov
8. Toshikatsu Hanada

Citations in the corpus

• Biological functions of microRNAs: a review (2011, background): “Under-expression of miR-146a contributes to alterations in the type I IFN pathway in lupus patients by targeting key signaling proteins [ 57 ].”
• Function of miR-146a in controlling Treg cell-mediated regulation of Th1 responses (2010, positive): “In addition to the aforementioned miR-146a targets, TRAF6 and IRAK1, a recent study has suggested that Stat1 is a miR-146a target in human PBMCs (Tang et al., 2009).”