Drug trapping in hERG K+ channels: (not) a matter of drug size?

By T. Linder, Harald Bernsteiner, P. Saxena, Florian Bauer, T. Erker, E. Timin, S. Hering, A. Stary-Weinzinger. 2015

510 citations recorded by the source corpus.

The hERG cavity can trap very bulky compounds, without perturbing normal gate closure.