Genome-wide atlas of gene expression in the adult mouse brain

By E. Lein, M. Hawrylycz, Nancy Ao, M. Ayres, Amy Bensinger, Amy Bernard, A. Boe, M. Boguski, Kevin S. Brockway, Emi J. Byrnes and 99 more. Nature, 2007

5,546 citations recorded by the source corpus.

Subfields: Biophysics, Molecular Biology

View Paper: https://www.semanticscholar.org/paper/62dbf5e9afe7ce59f0898f8aa61b1a38c057e7e9

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Citations in the corpus

Molecular, Spatial and Functional Single-Cell Profiling of the Hypothalamic Preoptic Region (2018, methodology): “5C, blue shaded rows), which is consistent with previous observations of high expression of Slc17a6 and Slc32a1 in these regions, respectively (35, 44).”
Overexpression of Fto leads to increased food intake and results in obesity (2010, background): “High Fto mRNA levels are observed in the brain, including the cerebellum, hippocampus and hypothalamu”
Functional organization of the transcriptome in human brain (2008, background): “To test this hypothesis, we cross-referenced genes that serve as markers for specific cell classes in the adult mouse brai”
An Atlas of Combinatorial Transcriptional Regulation in Mouse and Man (vol 140, pg 744, 2010) (2010, positive): “Messenger RNA in-situ hybridization analysis of mouse cerebellum, obtained from the Allen Brain Atlas (Lein et al., 2007), confirms that the interacting TFs are indeed expressed in cerebellum and that this localization is cerebellum-specific at single-cell resolution.”
lncRNAdb: a reference database for long noncoding RNAs (2010, methodology): “This extends the database through access to relative expression levels of both the lncRNAs and their contextually related transcripts in various public microarray experiments, such as NCode data and the GNF atlas (31), as well as the Allen Brain Atlas (32), which includes mouse brain in situ express”
Exome sequencing in sporadic autism spectrum disorders identifies severe de novo mutations (2011, neutral): “He is severely affected (CSS 10) with evidence of early onset and moderate ID. LAMC3 is not known to be involved in neuronal development; however, human microarray data have shown expression in many areas of the cortex and limbic system 25 .”
An atlas of combinatorial transcriptional regulation in mouse and man (2010, positive): “Messenger RNA in situ hybridization analysis of mouse cerebellum, obtained from the Allen Brain Atlas (Lein et al., 2007), confirms that the interacting TFs are indeed expressed in cerebellum and that this localization is cerebellum-specific at single-cell resolution.”
An atlas of the protein-coding genes in the human, pig, and mouse brain (2020, methodology): “In this open-access resource, transcriptomics data from three external sources—the Genotype-Tissue Expression (GTEx) portal (18), the Functional Annotation of Mammalian Genomes 5 (FANTOM5) project (19), and the AllenMouse Brain Atlas (3)—are presented together with RNA profiles and protein stainings”