Early diagnosis of myocardial infarction with sensitive cardiac troponin assays.

By T. Reichlin, W. Hochholzer, S. Bassetti, Stephan Steuer, C. Stelzig, S. Hartwiger, S. Biedert, N. Schaub, Christine Buerge, M. Potocki and 6 more. New England Journal of Medicine, 2009

1,708 citations recorded by the source corpus.

Subfields: Cardiology and Cardiovascular Medicine, Radiology, Nuclear Medicine and Imaging

View Paper: https://www.semanticscholar.org/paper/62adc01986253330d84b9a7ec55622658218e64a

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Cardiology and Cardiovascular Medicine

In Radiology, Nuclear Medicine and Imaging

T. Marwick

Citations in the corpus

Expert consensus for multimodality imaging evaluation of adult patients during and after cancer therapy: a report from the American Society of Echocardiography and the European Association of Cardiovascular Imaging. (2014, background): “Cardiac troponins are the gold-standard biomarkers for the diagnosis of myocardial injury.(172,173) Troponin I (TnI) is a sensitive and specific marker for myocardial injury in adults treated with anthracycline chemotherapy, and studies suggest that an elevation of troponin identifies patients at ri”
Recommendations for the use of cardiac troponin measurement in acute cardiac care. (2010, methodology): “when the recommended 99th percentile decision limit is used rather than higher values.(49,50,76) Even these minor elevations found with high performance novel research assays might be able to identify myocardial ischaemia in exercise stress tests as suggested by Sabatine et al.”
Analytical validation of a high-sensitivity cardiac troponin T assay. (2010, neutral): “More recently, the superior performance of high-sensitivity troponin T and troponin I assays for earlier detection of myocardial infarction compared to the less sensitive fourth-generation cTnT assay was confirmed in 2 larger trials (19, 20).”
Association of Troponin T Detected With a Highly Sensitive Assay and Cardiac Structure and Mortality Risk in the General Population (2010, positive): “Among patients with clinical presentations suspicious for MI, higher-sensitivity assays improve diagnostic sensitivity, particularly early after presentation, but reduce specificity.(12,36) When applied to patients with a high clinical suspicion for MI, the net result is improved accuracy.”
2014 AHA/ACC guideline for the management of patients with non-ST-elevation acute coronary syndromes: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines. (2014, background): “A negative cardiac troponin obtained with more sensitive cardiac troponin assays on admission confers a >95% negative predictive value for MI compared with high-sensitivity assays that confer a negative predictive value ≥ 99% (63-65).”
Expert consensus for multimodality imaging evaluation of adult patients during and after cancer therapy: a report from the American Society of Echocardiography and the European Association of Cardiovascular Imaging. (2014, background): “Cardiac troponins are the gold standard biomarkers for the diagnosis of myocardial injury.(172,173) Troponin I (TnI) is a sensitive and specific”