LAG-3, TIM-3 and VISTA Expression on Tumor-Infiltrating Lymphocytes in Oropharyngeal Squamous Cell Carcinoma—Potential Biomarkers for Targeted Therapy Concepts

By N. Wuerdemann, K. Pütz, H. Eckel, Rishabh Jain, C. Wittekindt, C. Huebbers, S. J. Sharma, C. Langer, S. Gattenlöhner, R. Büttner and 5 more. 2020

Subfields: Immunology, Oncology, Otorhinolaryngology

Citations in the corpus

• Impact of T Cell Exhaustion and Stroma Senescence on Tumor Cell Biology and Clinical Outcome of Head and Neck Squamous Cell Carcinomas (2024, unknown): “Wuerdemann et al. demonstrated that intratumoral CD8+ T cells in oral HNSCCs showed a significantly upregulated expression of LAG-3, TIM-3, and VISTA, and concluded that those proteins could be used as targets for new immunotherapeutic strategies [38].”