The proteasome: structure, function, and role in the cell.

By Julian Adams. 2003

589 citations recorded by the source corpus.

Subfields: Cell Biology, Molecular Biology, Oncology, Computational Biology & Bioinformatics

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Molecular Biology

1. Glaucius Oliva
2. L. Ferreira
3. Ricardo N Dos Santos
4. Adriano Defini Andricopulo
5. L. Gianni

In Oncology

1. L. Gianni

In Computational Biology & Bioinformatics

1. Glaucius Oliva
2. Adriano Defini Andricopulo
3. L. Ferreira
4. Ricardo N Dos Santos

Citations in the corpus

• Molecular Docking and Structure-Based Drug Design Strategies (2015, background): “The proteasome plays an essential role in eukaryotic metabolism by promoting the degradation of damaged and unnecessary proteins [209].”
• Anthracyclines: Molecular Advances and Pharmacologic Developments in Antitumor Activity and Cardiotoxicity (2004, background): “…the first two steps of mitochondrial death pathway triggered by oxidative stress in cardiac myocytes, which are priming (induced by H2O2 and consisting of progressive changes of the inner mitochondrial membrane in face of conserved membrane potential) and sudden depolarization (Akao et al., 2003).”
• Bortezomib as the First Proteasome Inhibitor Anticancer Drug: Current Status and Future Perspectives (2011, background): “From the E2- to the E3-bound substrate, the activated ubiquitin can then be transferred directly or via a third high energy thiol-ester intermediate [22, 33].”