Functional Living Trileaflet Heart Valves Grown In Vitro

By S. Hoerstrup, R. Sodian, S. Daebritz, Jun Wang, E. Bacha, David P. Martin, A. Moran, K. Guleserian, J. Sperling, S. Kaushal and 3 more. Circulation, 2000

673 citations recorded by the source corpus.

Subfields: Biomaterials, Cardiology and Cardiovascular Medicine, Surgery

View Paper: https://www.semanticscholar.org/paper/61a06254103bf67d71f3ee31bbafb3b2a4d9e265

How researchers see this paper

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In Biomaterials

1. G. Vunjak‐Novakovic
2. A. Atala
3. A. Mikos

In Surgery

1. A. Atala
2. A. Mikos

Citations in the corpus

• Engineering Complex Tissues (2006, positive): “Composite trileaflet valve-wall constructs fabricated from poly-4-hydroxybutyrate-coated polyglycolic acid scaffolds seeded with autologous bovine endothelial and carotid artery medial cells were cultured in vitro up to 14 days in a bioreactor that mimicked valve cyclical motions by providing pulsed”
• The emerging role of valve interstitial cell phenotypes in regulating heart valve pathobiology. (2007, background): “An exciting observation that supports the importance of physical forces in determining valve architecture and matrix organization is that tissue engineered heart valve constructs placed in the in vivo circulation change throughout time from a diffuse arrangement of cells within the matrix to a trila”