Prefrontal–striatal pathway underlies cognitive regulation of craving

By Hedy Kober, Peter Mende-Siedlecki, Ethan Kross, Jochen Weber, Walter Mischel, Carl L. Hart, Kevin N. Ochsner. Proceedings of the National Academy of Sciences of the United States of America, 2010

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Resting state functional connectivity in addiction: Lessons learned and a road ahead (2012, background): “Cognitive down-regulation of cue-induced cravings is accompanied by increased activity in TPN regions (e.g., lateral and posterior-medial PFC) and concomitant decreases in reward-related and DMN regions (e.g., ventral striatum, ACC and vmPFC) (Kober et al., 2010).”
Neural substrates of smoking cue reactivity: A meta-analysis of fMRI studies (2011, neutral): “…while the smokers performed a cognitive task (exclusion criterion 3; Artiges et al., 2009; Luijten et al., 2011; Nestor et al., 2011), and where the smokers were explicitly instructed to suppress their craving while the smoking cues were presented (exclusion criterion 4; Kober et al., 2010).”
Meditation experience is associated with differences in default mode network activity and connectivity (2011, methodology): “We found that relative to controls, meditators showed increased connectivity between PCC and task-positive regions, during resting-state baseline and all meditation conditions, including those involved in conflict monitoring, cognitive control, and working memory (dACC and dlPFC) (8, 32, 35, 38).”