The association of depression and anxiety with medical symptom burden in patients with chronic medical illness.

By W. Katon, E. Lin, K. Kroenke. General Hospital Psychiatry, 2007

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The epidemiology of depression across cultures (2013, background): “Less information is available on rates of depression treatment among patients with chronic physical disorders, but available evidence suggests that expanded treatment could be of considerable value (48).”
The Patient Health Questionnaire Somatic, Anxiety, and Depressive Symptom Scales: a systematic review. (2010, background): “Even disease-specific physical symptoms in patients with medical disorders may be explained as much by comorbid depression or anxiety as by the severity of the medical disorder [134].”
Depression, anxiety and somatization in primary care: syndrome overlap and functional impairment. (2008, background): “In addition, patients with chronic medical illness and comorbid depression or anxiety compared to those with chronic medical illness alone report significantly higher numbers of medical symptoms [56].”