A genome-wide association study identifies a gene network of ADAMTS genes in the predisposition to pediatric stroke

Citations in the corpus

• ADAMTS proteins in human disorders (2018, background): “ADAMTS12 is highly homologous to ADAMTS7 [24], and it may have a similar role in smooth muscle cells in association with vascular/hemostatic disorders [48, 49].”
• The procollagen N-proteinases ADAMTS2, 3 and 14 in pathophysiology. (2015, background): “9 × 10) between the ADAMTS2 gene and predisposition to pediatric stroke [39].”
• ADAMTS3 activity is mandatory for embryonic lymphangiogenesis and regulates placental angiogenesis (2015, unknown): “Other significant findings relating to potential functions are the relative resistance of Adamts2 mice to liver fibrosis [9], the infertility of Adamts2males [10], the expression of ADAMTS2 by activated macrophages [11], its anti-angiogenic properties [12] and its potential role in pediatric stroke ”