Micromachined impedance spectroscopy flow cytometer for cell analysis and particle sizing.

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Development of a microfluidic device for fluorescence activated cell sorting (2002, background): “Although several groups have demonstrated on-chip detection by means of impedance [6], fluorescence [7] and laser-based spectroscopy [8], there have been only few attempts at integration of active and passive micro-optical components.”
Single cell dielectric spectroscopy (2007, background): “21 1621–30 [69] Gawad S, Schild L and Renaud Ph 2001 Micromachined impedance spectroscopy flow cytometer for cell analysis and particle sizing Lab Chip 1 76–82 [70] Morgan H, Holmes D and Green N G 2006 High speed simultaneous single particle impedance and fluorescence analysis on a chip Curr.”
Blood-on-a-chip. (2005, methodology): “Although the spectral impedance of cells is an integrative measurement of membrane capacitance, cell size, cytoplasm resistance, and ionic channels, the device allows for differentiation between erythrocytes and other cell types (64).”
Dielectrophoresis-based sample handling in general-purpose programmable diagnostic instruments (2004, methodology): “A similar scheme has been demonstrated independently by Gawad [46], who also exploited DEP particle focusing in his microsensors.”