An Engineered R-Type Pyocin Is a Highly Specific and Sensitive Bactericidal Agent for the Food-Borne Pathogen Escherichia coli O157:H7

By D. Scholl, M. Cooley, Steven R. Williams, D. Gebhart, David Martin, A. Bates, R. Mandrell. 2009

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Programmable protein delivery with a bacterial contractile injection system (2023, positive): “A number of studies have demonstrated that modifications to the tail fibres of phages and other bacteria-targeting CISs are sufficient to alter target specificity in predictable ways 31–34 , indicating that these proteins are important determinants of target specificity in these systems.”
Engineering Phage Host-Range and Suppressing Bacterial Resistance through Phage Tail Fiber Mutagenesis (2019, background): “…have been undertaken to rationally expand the host-range of phages to combat resistance (Ando et al., 2015; Chen et al., 2017; Gebhart et al., 2017; Hawkins et al., 2008; Heilpern and Waldor, 2003; Lin et al., 2012; Nguyen et al., 2012; Scholl et al., 2009; Yoichi et al., 2005; Yosef et al., 2017).”