Success of the high‐dose/refuge resistance management strategy after 15 years of Bt crop use in North America

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Chapter Five – Progress Towards RNAi-Mediated Insect Pest Management (2014, background): “and deployed in the United States and elsewhere to delay the emergence of insect resistance to insect-protected crops expressing Bt insecticidal proteins (Gassmann et al., 2009; Huang et al., 2011; Tabashnik, 2008).”
Infestation of Wild and Ornamental Noncrop Fruits by Drosophila suzukii (Diptera: Drosophilidae) (2015, background): “A nontreated refuge could potentially delay the development of insecticide resistance (Huang et al. 2011).”
The New Integrated Pest Management Paradigm for the Modern Age (2019, unknown): “…pests developed resistance to transgenic crops with Bacillus thuringiensis toxic proteins (Tabashnik et al. 2013) and planting non-transgenic plants along with resistant plants has been recommend, among other strategies, to reduce the resistance development (Tang et al. 2001, Huang et al. 2011).”
Chapter Six – Detection and Mechanisms of Resistance Evolved in Insects to Cry Toxins from Bacillus thuringiensis (2014, background): “high-dose/refuge strategy has helped to delay pest resistance to Bt crops (Huang et al., 2011; Tabashnik et al., 2013).”