Limbic-predominant age-related TDP-43 encephalopathy (LATE): consensus working group report

By Peter T. Nelson, Dennis W. Dickson, John Q. Trojanowski, Clifford R. Jack Jr., Patricia A. Boyle, K. Arfanakis, Rosa Rademakers, I. Alafuzoff, J. Attems, Carol Brayne and 25 more. Brain : a journal of neurology, 2019

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Nelson et al. describe a recently recognized brain disorder that mimics the clinical features of Alzheimer’s disease: Limbic-predominant Age-related TDP-43 Encephalopathy (LATE). They review the literature and present consensus-based recommendations of an international, multidisciplinary working group, providing guidelines for diagnosis and staging of LATE neuropathological changes.

Subfields: Neurology, Physiology

View Paper: https://www.semanticscholar.org/paper/5f040d284db22da452a030db7262c7b34de50b5d