Chlorhexidine Arrests Subclinical Degradation of Dentin Hybrid Layers in vivo

By J. Hebling, D. Pashley, L. Tjäderhane, F. Tay. Journal of dentistry research, 2005

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Relationship between bond-strength tests and clinical outcomes. (2010, background): “[11] Hebling J, Pashley DH, Tjäderhane L, Tay FR.”
In vivo Preservation of the Hybrid Layer by Chlorhexidine (2007, background): “The ultrastructural features of microfibrillar strands (Zone 3) and multiple amorphous regions (Zone 4) suggest that these are remnant primary and/or secondary by-products of collagen breakdown (Hebling et al., 2005).”
State of the art etch-and-rinse adhesives (2010, neutral): “Three different groups of investigators have placed etch-and-rinse adhesives in class I cavities in which the peripheral enamel was acid-etched with 37% phosphoric acid for 15 s prior to bonding [22,28,31,32].”
Dental adhesion review: aging and stability of the bonded interface. (2008, background): “[102] showed that hybrid layers from chlorhexidinepre-treated teeth exhibited normal structural integrity of the collagen network compared to the progressive disintegration of the fibrillar collagen network detected in the control teeth.”