Inflammatory Markers and Onset of Cardiovascular Events: Results From the Health ABC Study

By M. Cesari, Brenda W. J. H. Penninx, Anne B. Newman, Stephen B. Kritchevsky, B. Nicklas, K. Sutton-Tyrrell, S. Rubin, Jingzhong Ding, Eleanor M. Simonsick, Tamara B. Harris and 1 more. Circulation, 2003

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Long-Term Interleukin-6 Levels and Subsequent Risk of Coronary Heart Disease: Two New Prospective Studies and a Systematic Review (2008, background): “]) because they are comparatively stable within individuals over time. By contrast, investigation of IL-6 in CHD has been relatively limited because of its shorter half-life (”
Psychological Stress in Childhood and Susceptibility to the Chronic Diseases of Aging: Moving Towards a Model of Behavioral and Biological Mechanisms (2011, background): “…persons, elevated rates of mortality in patients with acute coronary syndromes, and greater risk for all-cause mortality (Blake & Ridker, 2003; Cesari et al., 2003; Hashimoto et al., 2001; Kuo et al., 2005; Lindmark, Diderholm, Wallentin, & Siegbahn, 2001; Pradhan et al., 2002; Ridker,…”
Aging, frailty and age-related diseases (2010, background): “Most specifically, increased plasma IL-6 levels were found to be the most strongly associated with frailty (Ferrucci et al. 1999; Ershler and Keller 2000; Leng et al. 2002; Cesari et al. 2003; Reiner et al. 2009).”
Understanding the somatic consequences of depression: biological mechanisms and the role of depression symptom profile (2013, background): “Systemic elevations of these molecules in the absence of infection or tissue injury are considered abnormal and increase the onset of, for example, cardiovascular disease, diabetes and mortality [75,76].”