Haplotype Diversity and Linkage Disequilibrium at Human G6PD: Recent Origin of Alleles That Confer Malarial Resistance
By S. Tishkoff, Robert J. Varkonyi, Nelie Cahinhinan, S. Abbes, G. Argyropoulos, G. Destro‐Bisol, A. Drousiotou, Bruce Dangerfield, G. Lefranc, J. Loiselet and 7 more. Science, 2001
625 citations recorded by the source corpus.
Subfields: Genetics, Pediatrics, Perinatology and Child Health, Physiology
View Paper: https://www.semanticscholar.org/paper/5e9ed561487ffcddef5cb9e53df463e9c8246ba2
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In Genetics
- J. K. Pritchard
- Graham Coop
- Joseph K. Pickrell
- Nick Patterson
- David Reich
- Matthew Stephens
- Joel Hirschhorn
- Benjamin F. Voight
Citations in the corpus
- Genetic signatures of strong recent positive selection at the lactase gene. (2004, background): “…been demonstrated around the HbS allele in the b-globin gene HBB (MIM 141900) (Pagnier et al. 1984), the A Ϫ and Med alleles in G6PD (MIM 305900) (Tishkoff et al. 2001), the *O allele of the Duffy gene FY (MIM 110700) (Hamblin et al. 2002), and a promoter variant in the CD40 ligand gene TNFSF5…”
- Approximate Bayesian Computation in Evolution and Ecology (2010, background): “An early application of ABC was that by Tishkoff et al. (2001), who modeled selection at the G6PD locus in humans.”
- The Genetics of Human Adaptation: Hard Sweeps, Soft Sweeps, and Polygenic Adaptation (2010, positive): “Several of these are involved in malaria resistance, including the Duffy antigen protein (DARC) [23] and Glucose-6-phosphate dehydrogenase (G6PD) [24], as well as rarer mutations in the a- and b-globin genes that can lead to sickle cell anemia or thalassemias.”
- Evolutionary and Historical Aspects of the Burden of Malaria (2002, background): “in different human populations (188), and the sickle cell gene”