The Arabidopsis cytochrome P450 CYP707A encodes ABA 8′‐hydroxylases: key enzymes in ABA catabolism

By T. Kushiro, Masanori Okamoto, K. Nakabayashi, K. Yamagishi, Sayaka Kitamura, T. Asami, N. Hirai, T. Koshiba, Y. Kamiya, E. Nambara. EMBO Journal, 2004

985 citations recorded by the source corpus.

Subfields: Molecular Biology, Plant Science

View Paper: https://www.semanticscholar.org/paper/5e87f8587605f2bd4254b1dffa8975499b4d7d49

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Citations in the corpus

Transcriptional regulatory networks in cellular responses and tolerance to dehydration and cold stresses. (2006, background): “Among the 4 CYP707As, CYP707A3 is the major ABA-catabolizing enzyme and is mainly expressed in vegetative tissues.”
The role of ABA and MAPK signaling pathways in plant abiotic stress responses. (2014, background): “Cytochrome P450 monooxygenase (CYP707A) catalyzes the hydroxylation of ABA at the C-8′ to form unstable 8′-hydroxy ABA, which is subsequently converted to phaseic acid (PA) by spontaneous isomerization (Kushiro et al., 2004; Nambara and Marion-Poll, 2005; Saito et al., 2004).”
Implications of Abscisic Acid in the Drought Stress Tolerance of Plants (2020, background): “The ABA C-8′ hydroxylation reaction is mediated by the protein encoded by the CytochromeP450 (CYP)707A subfamily mono-oxygenase (CYP797A1-4) [99].”
Three Arabidopsis SnRK2 protein kinases, SRK2D/SnRK2.2, SRK2E/SnRK2.6/OST1 and SRK2I/SnRK2.3, involved in ABA signaling are essential for the control of seed development and dormancy. (2009, methodology): “Downloaded from https://academic.oup.com/pcp/article-abstract/50/7/1345/1889930 by guest on 30 July 2018 ( Kushiro et al. 2004 , Okamoto et al. 2006 ).”
Abscisic Acid Synthesis and Response (2013, methodology): “The ABA-8′-hydroxylases are encoded by the CYP707A family and were identified by a reverse genetics approach: candidate P450s were identified bioinformatically based on their phylogenic distribution and expression patterns, then functionally tested in yeast for ABA-8′-hydroxylase activity (Kushiro e”
A Novel Transcriptional Cascade Regulating Expression of Heat Stress Proteins during Seed Development of Arabidopsis (2007, methodology): “For imbibition experiments, seeds were imbibed under continuous light without stratification according to Kushiro et al. (2004).”
Abscisic acid biosynthesis and catabolism. (2005, background): “When ABA levels decrease during seed imbibition, concomitant increases in PA/DPA levels were observed in barley (52), lettuce (33), yellow-cedar (97), white pine (26), and Arabidopsis (62).”
The Role of Stress-Responsive Transcription Factors in Modulating Abiotic Stress Tolerance in Plants (2020, background): “The formation of ABA-glucose ester by UDP glucosyltransferase (UGT) is involved in ABA degradation, but ABA hydroxylation by cytochrome P450 monooxygenase 707A family members (CYP707As) appears to be largely responsible for ABA degradation [20].”
Abscisic acid and the control of seed dormancy and germination (2010, background): “3) (Ali-Rachedi et al., 2004; Kushiro et al., 2004; Millar et al., 2006; Okamoto et al., 2006; Liu et al., 2009; Preston et al., 2009).”
Abscisic Acid and Abiotic Stress Tolerance in Crop Plants (2016, background): “(Modified from, Taylor et al., 2000; Finkelstein and Rock, 2002; Tuteja, 2007; Mehrotra et al., 2014). for ABA metabolism (Kushiro et al., 2004; Saito et al., 2004).”
Guard Cell Signal Transduction Network: Advances in Understanding Abscisic Acid, CO2, and Ca2+ Signaling (2010, background): “The CYTOCHROME P450, FAMILY 707, SUBFAMILY A genes CYP707A1 to A4, encoding ABA 8′-hydroxylases, are induced by rehydration of dehydrated plants (89).”
Seed dormancy and the control of germination. (2006, background): “• ABA deficiency during seed development is associated with absence of primary dormancy in the mature seed, whereas overexpression of ABA biosynthesis genes can increase seed ABA content and enhance seed dormancy or delay germination (e.g. Finkelstein et al., 2002; Nambara & Marion-Poll, 2003; Kushi”