Patients with hippocampal amnesia cannot imagine new experiences

By Demis Hassabis, Dharshan Kumaran, Seralynne D. Vann, Eleanor A. Maguire. 2007

1,378 citations recorded by the source corpus.

Subfields: Cognitive Neuroscience, Developmental and Educational Psychology

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In Developmental and Educational Psychology

Citations in the corpus

Hippocampal Replay is Not a Simple Function of Experience (2010, background): “The hippocampal formation has been shown to be important for the imagination of novel situations (Hassabis et al., 2007), and has been implicated in self-projection (Gelbard-Sagiv et al.”
Hippocampal place cells construct reward related sequences through unexplored space (2015, background): “Preplay of a visible, unvisited environment that has motivational relevance to an animal accords with various reports from neuropsychological and imaging studies indicating a crucial role for the hippocampus in processing future goals (Spiers and Barry, 2015), imagination, and future thinking (Hassa”
Remembering the past to imagine the future: the prospective brain (2007, positive): “Thinking about the perspectives of others (theory of mind) also appears to use the core brain system 40 , as do certain forms of navigation 20,32,41 .”
The Successor Representation and Temporal Context (2012, background): “Damage to this network, particularly the hippocampus, impairs both autobiographical memory and episodic future thinking (Hassabis, Kumaran, Vann, & Maguire, 2007 ).”
The Kanerva Machine: A Generative Distributed Memory (2018, result): “This phenomenon is consistent with the observation of constructive memory neuroscience experiments (Hassabis et al., 2007).”
Social learning of fear (2007, background): “Like recollection of the past, projection into the future is impaired after hippocampal lesion”
Collective future thought: Concept, function, and implications for collective memory studies (2016, neutral): “; Hassabis et al., 2007; Tulving, 1985; but see Squire et al., 2010).”
The Role of Hippocampal Replay in Memory and Planning (2018, background): “and are unable to describe rich fictitious scenes [26].”
Memory and the Sense of Personal Identity (2012, background): “…to consciously plan for his personal future, an ability, as we have noted, widely considered causally linked to the presence of intact episodic memory function (e.g. Hassabis et al. 2007; Klein, Loftus, and Kihlstrom 2002; Tulving 1985; for review see Klein 2010; Suddendorf and Corballis 2007).”
Navigating cognition: Spatial codes for human thinking (2018, background): “In humans, hippocampal simulations have been linked to the construction of imaginary scenarios (12, 62, 63, 73)— an ability impaired in patients with hippocampal lesions (130).”