Pathways of cellular proteostasis in aging and disease

By C. L. Klaips, G. Jayaraj, F. Hartl. Journal of Cell Biology, 2018

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Klaips et al. outline the pathways and molecular mechanisms of cellular protein homeostasis, or proteostasis, and discuss how a decline in proteostasis during aging contributes to disease.

Subfields: Cell Biology, Cellular and Molecular Neuroscience, Molecular Biology

View Paper: https://www.semanticscholar.org/paper/5e335911071f7e772163e4734f90aafb65d60bef