Identification of BMP9 and BMP10 as functional activators of the orphan activin receptor-like kinase 1 (ALK1) in endothelial cells.
By L. David, C. Mallet, S. Mazerbourg, J. Feige, S. Bailly. Blood, 2007
693 citations recorded by the source corpus.
Subfields: Genetics, Molecular Biology
View Paper: https://www.semanticscholar.org/paper/5dd80ae2c3ad11a00542296cec6e7aae3cae12c4
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In Genetics
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Citations in the corpus
- Cellular and Molecular Basis of Pulmonary Arterial Hypertension (2009, background): “This important finding might provide a mechanism for the rare occurrence of severe PAH in some families with hereditary hemorrhagic telangiectasia due to ALK-1 mutations (82).”
- TGF-β and the TGF-β Family: Context-Dependent Roles in Cell and Tissue Physiology. (2016, background): “For example, BMP-9 and BMP-10, which were identified as ligands of the ALK-1 receptor (David et al. 2007), play essential roles in the maintenance of homeostasis of vascular system and heart development (David et al.”