The Design of Scaffolds for Use in Tissue Engineering. Part I. Traditional Factors

By Shoufeng Yang, K. Leong, Z. Du, C. K. Chua. Tissue engineering, 2001

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Investigation of the mechanical properties and porosity relationships in fused deposition modelling‐fabricated porous structures (2006, methodology): “Inconsistency in pore size reproduction, irregularity in pore distribution, indispensible usage of toxic organic solvents, labour-intensive and deficiency in scaffolds' mechanical strength are some of the problems commonly associated with these fabrication techniques ( Yang et al. , 2001”
A Review: Electrospinning of Biopolymer Nanofibers and their Applications (2008, background): “98 Non‐woven fibrous mats could conceivably resemble the extracellular matrix; however, it is also necessary that the effects that an artificial matrix have on cell growth, proliferation, and differentiation be thoroughly investigated.”
Alginate-Based Biomaterials for Regenerative Medicine Applications (2013, methodology): “Compared to the others, freeze-drying is the easiest method to fabricate porous scaffolds [92–94].”
Scaffold development using selective laser sintering of polyetheretherketone-hydroxyapatite biocomposite blends. (2003, background): “Scaffold characteristics and properties such as porosity, surface area to volume ratio, pore size, pore interconnectivity, structural strength, shape (or overall geometry) and biocompatibility [5–9] are often considered to be critical factors in their design and fabrication.”