The preclinical phase of alzheimer disease: A 22-year prospective study of the Framingham Cohort.

By M. Elias, A. Beiser, P. Wolf, Rhoda Au, Roberta F. White, R. D’Agostino. Archives of Neurology, 2000

771 citations recorded by the source corpus.

Subfields: Experimental and Cognitive Psychology, Psychiatry and Mental health, Surgery

View Paper: https://www.semanticscholar.org/paper/246cfd02e22e3e8bcddcc94c895683f3c19eb14e

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Citations in the corpus

What is normal in normal aging? Effects of Aging, Amyloid and Alzheimer’s Disease on the Cerebral Cortex and the Hippocampus (2014, background): “Subtle cognitive symptoms have been identified more than 10 years before dementia diagnosis (Elias et al., 2000), and the currently popular hypothetical biomarker model suggests that brain changes are detectable before the first cognitive symptoms (Jack et al., 2010a, 2013).”
Inequalities in dementia incidence between six racial and ethnic groups over 14 years (2016, background): “Although HCHS/SOL did not assess dementia, low performance on neuropsychological tests in population samples strongly predicts future dementia risk [35].”
Cerebral small-vessel disease and decline in information processing speed, executive function and memory. (2005, background): “A diagnosis of dementia is often preceded by a preclinical phase of many years (Elias et al., 2000).”
Brain reserve and dementia: a systematic review (2005, background): “As shown in Table 1, the majority of brainreserve studies have used education as a brain-reserve measure (Hebert et al. 1992; Bickel & Cooper, 1994; Paykel et al. 1994; Stern et al. 1994; Cobb et al. 1995; Yoshitake et al. 1995; Persson & Skoog, 1996; Evans et al. 1997; Schmand et al. 1997; Ott et a”
Hearing Loss and Cognition in the Baltimore Longitudinal Study of Aging (2011, background): “Results from longitudinal studies have generally demonstrated that decrements in both measures of memory (Elias et al., 2000; Grober, Hall, Lipton, et al., 2008; Linn et al., 1995; Rubin et al., 1998) and executive function (Chen et al.”
Cognitive impairment in preclinical Alzheimer's disease: a meta-analysis. (2005, result): “These findings are consistent with claims made by many investigators in this field (e.g., Bäckman, Small, & Fratiglioni, 2001; Elias et al., 2000; Grober & Kawas, 1997; Linn et al., 1995; B. J. Small, Herlitz, et al., 1997 ) that episodic memory impairment is a cardinal feature of an impending…”
Late-life engagement in social and leisure activities is associated with a decreased risk of dementia: a longitudinal study from the Kungsholmen project. (2002, background): “Second, recent reports on the preclinical stages of Alzheimer’s disease have shown deficits in specific cognitive domains in subjects who developed dementia 7 (29, 30) and 10 (31) years later.”