A variant associated with nicotine dependence, lung cancer and peripheral arterial disease
By Thorgeir E. Thorgeirsson, F. Geller, P. Sulem, T. Rafnar, Anna K. Wiste, K. Magnússon, A. Manolescu, G. Thorleifsson, Hreinn Stefansson, A. Ingason and 47 more. Nature, 2008
1,546 citations recorded by the source corpus.
Subfields: Molecular Biology
View Paper: https://www.semanticscholar.org/paper/5cfa7b2369c3351b0ce6f50dc8ce8e8ea64394bf
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In Molecular Biology
- Charles Auffray
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- Leroy Hood
- Zhu Chen
- Shaker A. Mousa
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Citations in the corpus
- A SNP in a let-7 microRNA complementary site in the KRAS 3′UTR Increases Non-Small Cell Lung Cancer Risk (2008, background): “The mechanism of lung cancer predisposition caused by these SNPs is controversial but is hypothesized to be through affects on a nicotine receptor (35, 36).”
- Systems medicine: the future of medical genomics and healthcare (2009, background): “significant problems with signal-to-noise ratios that still severely limit the conclusions that can be drawn from such studies, progress has been made in identifying susceptibility loci involved in, for example, diabetes [161-163], obesity [164], and breast or lung cancer [165-167].”
- The ENIGMA Consortium: large-scale collaborative analyses of neuroimaging and genetic data (2014, neutral): “…disorder (Sklar et al. 2011; Cichon et al. 2011) as well as obesity (Yang et al. 2012), alcohol drinking (Schumann et al. 2011), tobacco smoking (Thorgeirsson et al. 2008), cardiovascular disease (CARDIoGRAMplusC4D Consortium et al. 2013), osteoporosis (Estrada et al. 2012), prevalent…”
- The nature of nurture: Effects of parental genotypes (2017, background): “While it is not a novel concept that genes can affect the environment (23, 34, 35), the”
- A Genome-Wide Association Study in Chronic Obstructive Pulmonary Disease (COPD): Identification of Two Major Susceptibility Loci (2009, background): “Another lung cancer report by Amos and colleagues [12] did show weak evidence for association with smoking behavior, while a further report by Thorgeirsson and colleagues[14] showed very strong association with smoking behavior.”