Cardiac fibroblast-derived microRNA passenger strand-enriched exosomes mediate cardiomyocyte hypertrophy.
By C. Bang, S. Batkai, Seema Dangwal, Shashi K. Gupta, A. Foinquinos, A. Holzmann, A. Just, J. Remke, K. Zimmer, A. Zeug and 11 more. Journal of Clinical Investigation, 2014
918 citations recorded by the source corpus.
Subfields: Cardiology and Cardiovascular Medicine, Molecular Biology
View Paper: https://www.semanticscholar.org/paper/5cf24ab89a5d3fb516235dc61f14d269a4a22d15
How researchers see this paper
The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.
In Cardiology and Cardiovascular Medicine
In Molecular Biology
- Amanda Birmingham
- Maria-Teresa Piccoli
- J. Beermann
- Jerrold M. Olefsky
- J. Viereck
- Thomas Thum
- P. Calder
Citations in the corpus
- Adipose Tissue Macrophage-Derived Exosomal miRNAs Can Modulate In Vivo and In Vitro Insulin Sensitivity. (2017, positive): “Evidence also exists that these Exos can be taken up into neighboring or distant cell types to modulate the function of recipient cells (Bang et al., 2014; Costa-Silva et al., 2015; Fong et al., 2015; Zhang et al., 2015b).”
- Non-coding RNAs in Development and Disease: Background, Mechanisms, and Therapeutic Approaches. (2016, background): “As a matter of fact, it has been recently shown that miR21* is produced by CFs, incorporated into exosomes, and secreted in the extracellular environment, inducing cardiomyocyte hypertrophy via its paracrine effect on these cells (10).”
- The exosome journey: from biogenesis to uptake and intracellular signalling (2021, background): “They influence a broad range of physiological processes such as immune responses [7], tissue repair [8, 9], stem cell maintenance [10], central nervous system (CNS) communication [6] and pathological processes in cardiovascular diseases [11, 12], neurodegeneration [13], cancer [14] and inflammation ”