TANGOing along the protein secretion pathway

By C. Rabouille, Vangelis Kondylis. 2006

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Although the organization and functions of the constitutive secretory pathway have been intensively studied for decades, a recent genome-wide RNAi screen in Drosophila cells has identified about 100 genes encoding novel so-called TANGO proteins (for transport and Golgi organization) that may be direct regulators of various aspects of protein exocytosis or secretion.

Subfields: Cell Biology, Molecular Biology

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