A ribosome-bound quality control complex triggers degradation of nascent peptides and signals translation stress.

By Onn Brandman, Jacob Stewart-Ornstein, Daisy Wong, A. Larson, C. C. Williams, Gene‐Wei Li, Sharleen Zhou, D. King, P. Shen, Jimena Weibezahn and 5 more. Cell, 2012

609 citations recorded by the source corpus.

Subfields: Immunology, Molecular Biology

View Paper: https://www.semanticscholar.org/paper/5be17f100ed49e5677191ad210d7f889161b5054

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Molecular Biology

1. Carol A. Gross
2. D. Burkhardt
3. Gene‐Wei Li
4. Mark P. Jedrychowski
5. Steven P. Gygi
6. Jonathan S. Weissman
7. Mahmoud Ghandi
8. William R. Sellers

Citations in the corpus

• Quantifying absolute protein synthesis rates reveals principles underlying allocation of cellular resources. (2014, background): “It is a general tool for monitoring expression as well as enabling identification of novel translational events (Brandman et al., 2012; Brar et al., 2012; Ingolia et al., 2011; Li et al., 2012; Oh et al., 2011; Stern-Ginossar et al., 2012).”
• Quantitative Proteomics of the Cancer Cell Line Encyclopedia (2020, background): “The Ribosomal Quality Control (RQC) complex surveys newly synthesized proteins exiting the ribosome (Brandman et al., 2012).”