A Common Allele on Chromosome 9 Associated with Coronary Heart Disease
By R. McPherson, A. Pertsemlidis, Nihan Kavaslar, A. Stewart, R. Roberts, D. Cox, David A. Hinds, Len A. Pennacchio, A. Tybjaerg-hansen, A. Folsom and 3 more. Science, 2007
1,486 citations recorded by the source corpus.
Subfields: Genetics, Molecular Biology, Rheumatology
View Paper: https://www.semanticscholar.org/paper/5aaafa212640191412c214f54eb5e044599f05ba
How researchers see this paper
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In Genetics
- Sekar Kathiresan
- Eric E. Schadt
- A. Khera
- M. Blasco
- John D. Storey
- Andrew Kasarskis
- P. Natarajan
- Aldons J. Lusis
In Molecular Biology
- Manuel Serrano
- Eric E. Schadt
- Eric S. Lander
- Aldons J. Lusis
- Stacey Gabriel
- Mete Civelek
- M. Blasco
- M. Collado
In Rheumatology
Citations in the corpus
- Long non-coding RNA ANRIL is required for the PRC2 recruitment to and silencing of p15INK4B tumor suppressor gene (2010, background): “Recent genome-wide association studies have linked common single-nucleotide polymorphisms in 9p21 region that is independently associated with both type II diabetes and coronary heart disease (Helgadottir et al., 2007; McPherson et al., 2007; Saxena et al., 2007; Scott et al., 2007).”
- Cellular senescence in cancer and aging. (2007, positive): “Recently, genetic variants in the INK4a/ARF locus have been linked to various age-associated diseases, including general frailty, heart failure, and type 2 diabetes (Helgadottir et al., 2007; McPherson et al., 2007; Melzer et al., 2007; Saxena et al., 2007; Scott et al., 2007; Zeggini et al., 2007).”
- CD47 blocking antibodies restore phagocytosis and prevent atherosclerosis (2016, background): “Furthermore, the top cardiovascular locus identified by genome-wide association studies surprisingly resides near an important tumour suppressor locus 27 , which in turn regulates SMC efferocytosis 17 .”