Molecular mechanisms of resistance and toxicity associated with platinating agents.

By C. Rabik, M. Dolan. Cancer Treatment Reviews, 2007

1,562 citations recorded by the source corpus.

Subfields: Molecular Biology, Plant Science

View Paper: https://www.semanticscholar.org/paper/5a3a6b1a1e5816490854ea9b113e820ec8549b8a

How researchers see this paper

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In Molecular Biology

1. Thomas Helleday
2. Ricky A. Sharma
3. Sumit Ghosh

In Plant Science

1. Sumit Ghosh

Citations in the corpus

• DNA repair pathways as targets for cancer therapy (2008, background): “It has been shown in preclinical models that the major cisplatin intra-strand crosslinks formed in DNA are recognized and repaired by the mammalian NER pathwa”
• Cisplatin: The first metal based anticancer drug. (2019, background): “But majority accept that 1,2-intrastrand adducts induce cytotoxicity more effectively than 1,3intra adducts [12,76,81].”