Childhood Incident Asthma and Traffic-Related Air Pollution at Home and School
By R. McConnell, T. Islam, K. Shankardass, Michael Jerrett, F. Lurmann, F. Gilliland, J. Gauderman, E. Avol, N. Künzli, Ling Yao and 2 more. Environmental Health Perspectives, 2010
598 citations recorded by the source corpus.
Background Traffic-related air pollution has been associated with adverse cardiorespiratory effects, including increased asthma prevalence. However, there has been little study of effects of traffic exposure at school on new-onset asthma. Objectives We evaluated the relationship of new-onset asthma with traffic-related pollution near homes and schools. Methods Parent-reported physician diagnosis of new-onset asthma (n = 120) was identified during 3 years of follow-up of a cohort of 2,497 kindergarten and first-grade children who were asthma- and wheezing-free at study entry into the Southern California Children’s Health Study. We assessed traffic-related pollution exposure based on a line source dispersion model of traffic volume, distance from home and school, and local meteorology. Regional ambient ozone, nitrogen dioxide (NO2), and particulate matter were measured continuously at one central site monitor in each of 13 study communities. Hazard ratios (HRs) for new-onset asthma were scaled to the range of ambient central site pollutants and to the residential interquartile range for each traffic exposure metric. Results Asthma risk increased with modeled traffic-related pollution exposure from roadways near homes [HR 1.51; 95% confidence interval (CI), 1.25–1.82] and near schools (HR 1.45; 95% CI, 1.06–1.98). Ambient NO2 measured at a central site in each community was also associated with increased risk (HR 2.18; 95% CI, 1.18–4.01). In models with both NO2 and modeled traffic exposures, there were independent associations of asthma with traffic-related pollution at school and home, whereas the estimate for NO2 was attenuated (HR 1.37; 95% CI, 0.69–2.71). Conclusions Traffic-related pollution exposure at school and homes may both contribute to the development of asthma.
Subfields: Health, Toxicology and Mutagenesis, Speech and Hearing
View Paper: https://www.semanticscholar.org/paper/5a1623e1d03446a4718e987eacf8a08afbaec834
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Citations in the corpus
- Spatial Foundations of Inequality: A Conceptual Model and Empirical Overview (2017, background): “We know, for example, how variations in air pollution can be associated with a range of health outcomes (McConnell et al. 2010; Lovasi et al. 2011).”
- Review of evidence on health aspects of air pollution – REVIHAAP Project. Technical Report. World Health Organization Regional Office for Europe 2013 (2013, result): “by Meng et al. (2012) also varied, both finding (Rijnders et al.”
- Health effects of particulate air pollution: A review of epidemiological evidence (2011, background): “More recent analyses of The California Children’s Health Study also showed that new-onset asthma is associated with traffic-related pollution near homes and schools (McConnell et al., 2010).”