Biosynthesis of metallic nanoparticles using plant derivatives and their new avenues in pharmacological applications – An updated report
By Palaniselvam Kuppusamy, M. Yusoff, G. Maniam, N. Govindan. Saudi Pharmaceutical Journal, 2014
947 citations recorded by the source corpus.
The field of nanotechnology mainly encompasses with biology, physics, chemistry and material sciences and it develops novel therapeutic nanosized materials for biomedical and pharmaceutical applications. The biological syntheses of nanoparticles are being carried out by different macro–microscopic organisms such as plant, bacteria, fungi, seaweeds and microalgae. The biosynthesized nanomaterials have been effectively controlling the various endemic diseases with less adverse effect. Plant contains abundant natural compounds such as alkaloids, flavonoids, saponins, steroids, tannins and other nutritional compounds. These natural products are derived from various parts of plant such as leaves, stems, roots shoots, flowers, barks, and seeds. Recently, many studies have proved that the plant extracts act as a potential precursor for the synthesis of nanomaterial in non-hazardous ways. Since the plant extract contains various secondary metabolites, it acts as reducing and stabilizing agents for the bioreduction reaction to synthesized novel metallic nanoparticles. The non-biological methods (chemical and physical) are used in the synthesis of nanoparticles, which has a serious hazardous and high toxicity for living organisms. In addition, the biological synthesis of metallic nanoparticles is inexpensive, single step and eco-friendly methods. The plants are used successfully in the synthesis of various greener nanoparticles such as cobalt, copper, silver, gold, palladium, platinum, zinc oxide and magnetite. Also, the plant mediated nanoparticles are potential remedy for various diseases such as malaria, cancer, HIV, hepatitis and other acute diseases.
Subfields: Complementary and alternative medicine, Materials Chemistry, Nutrition and Dietetics
View Paper: https://www.semanticscholar.org/paper/5983d0860dfbff5479c7fe69c189ac0e55aa269b
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Citations in the corpus
- Green Synthesis of Metallic Nanoparticles: Applications and Limitations (2021, background): “, in the biomaterials act as reducing and capping agents for the synthesis of NPs from its metal salt precursors [19].”
- Silver nanoparticles: Synthesis, medical applications and biosafety (2020, methodology): “The biological method usually relies on macromolecular substances in bacteria, fungi, and algae [16], such as exopolysaccharide, cellulose, and enzymes, and organic components in plant extracts such as enzymes, alcohol, flavonoids, alkaloids, quinines, terpenoids, phenolic compounds [16, 56-59].”