Engineering soluble proteins for structural genomics
By J. Pedelacq, Emily Piltch, E. Liong, J. Berendzen, Chang-Yub Kim, Beom-Seop Rho, M. Park, T. C. Terwilliger, G. Waldo. 2002
185 citations recorded by the source corpus.
Subfields: Materials Chemistry, Molecular Biology
How researchers see this paper
The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.
In Molecular Biology
- H. P. Sørensen
- Alex Hawkins-Hooker
- Sebastien Baur
- Guillaume Couairon
- K. Mortensen
- F. Depardieu
- David Bikard
- A. Chen
Citations in the corpus
- Generating functional protein variants with variational autoencoders (2020, background): “This phenomenon is a challenge in a wide range of applications, from the 253 production of protein therapeutics to the study of protein biochemistry and structure, leading to 254 interest in engineering of increased-solubility variants [47].”
- Advanced genetic strategies for recombinant protein expression in Escherichia coli. (2005, background): “This approach evolved three insoluble proteins includingPyrobaculum aerophilum methyl transferase, tartrate dehydratase -subunit and nucleoside diphosphate kinase to be 50, 95 and 90% soluble, respectively (Pedelacq et al., 2002).”