Disrupted cardiac development but normal hematopoiesis in mice deficient in the second CXCL12/SDF-1 receptor, CXCR7

By F. Sierro, C. Biben, Laura Martínez-Muñoz, M. Mellado, R. Ransohoff, Meizhang Li, Blanche Woehl, H. Leung, J. Groom, M. Batten and 4 more. Proceedings of the National Academy of Sciences of the United States of America, 2007

672 citations recorded by the source corpus.

Subfields: Hematology, Molecular Biology, Oncology

View Paper: https://www.semanticscholar.org/paper/58e747834297fe30c74a77957afca8e6529b9704

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In Molecular Biology

1. Jianhua Wang
2. R. Taichman

In Oncology

1. A. Zlotnik
2. O. Yoshie
3. Jianhua Wang
4. R. Taichman

Citations in the corpus

• CXCL12/CXCR4/CXCR7 Chemokine Axis and Cancer Progression (2010, background): “Another role for the receptor is that it may serve as a co-receptor for CXCR4 [59, 60] and enhance CXCL12mediate G-protein signaling [59], as the two receptors form heterodimers in the context of overexpression in transiently transfected cells.”
• International Union of Basic and Clinical Pharmacology. LXXXIX. Update on the Extended Family of Chemokine Receptors and Introducing a New Nomenclature for Atypical Chemokine Receptors (2014, neutral): “This indicates that the lethal cardiac phenotype is not caused by a defective Cxcl11/Ackr3 interaction and that the critical ligand is Cxcl12 or another as yet undiscovered factor (Sierro et al., 2007).”
• The Chemokine Superfamily Revisited (2012, positive): “Other studies have documented that the CXCL12-CXCR4 axis plays pivotal roles in homing of various stem cells to particular places of the embryo during development.”