Post-acute COVID-19 syndrome
By Ani Nalbandian, K. Sehgal, Aakriti Gupta, Mahesh V. Madhavan, C. McGroder, J. Stevens, Joshua R. Cook, A. Nordvig, D. Shalev, Tejasav S. Sehrawat and 24 more. Nature Medicine, 2021
4,179 citations recorded by the source corpus.
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the pathogen responsible for the coronavirus disease 2019 (COVID-19) pandemic, which has resulted in global healthcare crises and strained health resources. As the population of patients recovering from COVID-19 grows, it is paramount to establish an understanding of the healthcare issues surrounding them. COVID-19 is now recognized as a multi-organ disease with a broad spectrum of manifestations. Similarly to post-acute viral syndromes described in survivors of other virulent coronavirus epidemics, there are increasing reports of persistent and prolonged effects after acute COVID-19. Patient advocacy groups, many members of which identify themselves as long haulers, have helped contribute to the recognition of post-acute COVID-19, a syndrome characterized by persistent symptoms and/or delayed or long-term complications beyond 4 weeks from the onset of symptoms. Here, we provide a comprehensive review of the current literature on post-acute COVID-19, its pathophysiology and its organ-specific sequelae. Finally, we discuss relevant considerations for the multidisciplinary care of COVID-19 survivors and propose a framework for the identification of those at high risk for post-acute COVID-19 and their coordinated management through dedicated COVID-19 clinics. A comprehensive review of the current literature on post-acute COVID-19, also referred to as long COVID, its pathophysiology and its organ-specific sequelae highlights the need for multidisciplinary follow-up and care of COVID-19 survivors.
Subfields: Clinical Psychology, Infectious Diseases, Neurology
View Paper: https://www.semanticscholar.org/paper/58bb9b82503e7a9a4e2a28592969b0fe5165f35e
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In Clinical Psychology
In Infectious Diseases
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Citations in the corpus
- Distinguishing features of long COVID identified through immune profiling (2022, methodology): “Additionally, all participants had electronic 642 health records reviewed by study clinicians following enrollment and were subsequently excluded prior to 643 analyses for the following reasons: (1) current pregnancy, (2) immunosuppression equivalent to or 644 exceeding prednisone 5 mg daily, (3) ac”
- Long COVID or post-COVID-19 syndrome: putative pathophysiology, risk factors, and treatments (2021, background): “[14] Post-acute COVID-19 syndrome Symptoms lasting for> 4weeks after the first symptom onset.”