Integration of Brassinosteroid Signal Transduction with the Transcription Network for Plant Growth Regulation in Arabidopsis

By Yu Sun, Xi-Ying Fan, Dong-Mei Cao, Kun He, Wenqiang Tang, Jia-Ying Zhu, Junxian He, Ming-Yi Bai, Shengwei Zhu, Eunkyoo Oh and 6 more. Developmental Cell, 2010

868 citations recorded by the source corpus.

SUMMARY Brassinosteroids (BRs) regulate a wide range of developmental and physiological processes in plants through a receptor-kinase signaling pathway that controls the BZR transcription factors. Here we use transcript profiling and chromatin-immunoprecipitation microarray (ChIP-chip) experiments to identify 953 BR-regulated BZR1 target (BRBT) genes. Functional studies of selected BRBTs further demonstrate roles in BR-promotion of cell elongation. The BRBT genes reveal numerous molecular links between the BR signaling pathway and downstream components involved in developmental and physiological processes. Furthermore, the results reveal extensive crosstalk between BR and other hormonal and light signaling pathways at multiple levels. For example, BZR1 not only controls the expression of many signaling components of other hormonal and light pathways, but also co-regulates common target genes with light-signaling transcription factors. Our results provide a genomic map of steroid hormone actions in plants, which reveals a regulatory network that integrates hormonal and light signaling pathways for plant growth regulation.

Subfields: Molecular Biology, Plant Science

View Paper: https://www.semanticscholar.org/paper/588e9e413312264d27f9d576644a9a5c12028a71

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Molecular Biology

1. Sunghwa Choe
2. Jonathan D. G. Jones
3. Yuhee Chung
4. Yanhai Yin

In Plant Science

1. M. Grant
2. Alexandre Robert-Seilaniantz
3. Sunghwa Choe
4. Jonathan D. G. Jones
5. Yuhee Chung
6. Yanhai Yin
7. Martin Heil
8. Olivier Voinnet

Citations in the corpus

• Comprehending crystalline β-carotene accumulation by comparing engineered cell models and the natural carotenoid-rich system of citrus (2011, neutral): “However, two recent reports profiling direct target genes for BZR1 or BES1 did not identify ABS1 as a direct target of either BZR1 or BES1 (Sun et al., 2010; Yu et al., 2011).”
• Brassinosteroids: Multidimensional Regulators of Plant Growth, Development, and Stress Responses[OPEN] (2019, background): “These studies revealed hundreds of 209 BES1/BZR1-targeted TFs (BTFs) that are regulated by BRs (Sun et al., 2010; Yu et al., 2011; 210 Guo et al., 2013).”
• Hormone crosstalk in plant disease and defense: more than just jasmonate-salicylate antagonism. (2011, background): “BZR1 is able to repress the expression of genes directly involved in defense against pathogens such as FLS2 and SNC1 (185).”
• The Regulation of Brassinosteroid Biosynthesis in Arabidopsis (2013, background): “Recently, a genome-wide ChIP-chip analysis using a BZR1-CFP transgenic line identified 953 BRBT (BR Response BZR1 Target) genes and proposed the existence of BZR1-mediated crosstalk between BR and other signaling pathways (Sun et al., 2010).”