Depression and cancer mortality: a meta-analysis
By M. Pinquart, P. Duberstein. Psychological Medicine, 2010
1,013 citations recorded by the source corpus.
Background The goal of the present study was to analyze associations between depression and mortality of cancer patients and to test whether these associations would vary by study characteristics. Method Meta-analysis was used for integrating the results of 105 samples derived from 76 prospective studies. Results Depression diagnosis and higher levels of depressive symptoms predicted elevated mortality. This was true in studies that assessed depression before cancer diagnosis as well as in studies that assessed depression following cancer diagnosis. Associations between depression and mortality persisted after controlling for confounding medical variables. The depression–mortality association was weaker in studies that had longer intervals between assessments of depression and mortality, in younger samples and in studies that used the Beck Depression Inventory as compared with other depression scales. Conclusions Screening for depression should be routinely conducted in the cancer treatment setting. Referrals to mental health specialists should be considered. Research is needed on whether the treatment of depression could, beyond enhancing quality of life, extend survival of depressed cancer patients.
Subfields: Cardiology and Cardiovascular Medicine, Oncology, Surgery
View Paper: https://www.semanticscholar.org/paper/584d0ec5d047d975e00f2bdb7150df9677cca6f1
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In Oncology
Citations in the corpus
- Screening, assessment, and care of anxiety and depressive symptoms in adults with cancer: an American Society of Clinical Oncology guideline adaptation. (2014, background): “18).(53,72) Two studies have now documented increased rates of suicide among populations of longterm breast and testicular cancer survivors.”
- Anxiety and depression after cancer diagnosis: prevalence rates by cancer type, gender, and age. (2012, background): “, 2008), and carries an elevated risk of mortality (Pinquart and Duberstein, 2010; Satin et al., 2009).”
- Psilocybin produces substantial and sustained decreases in depression and anxiety in patients with life-threatening cancer: A randomized double-blind trial (2016, background): “Depression is an independent risk factor of early death in cancer patients (Arrieta et al., 2013; Pinquart and Duberstein, 2010).”
- Depression and anxiety in relation to cancer incidence and mortality: a systematic review and meta-analysis of cohort studies (2019, background): “Furthermore, other intervening factors are likely to account for mortality as the survival time extended [82].”