A Phase I Clinical Trial of the Treatment of Crohn’s Fistula by Adipose Mesenchymal Stem Cell Transplantation

By D. García-Olmo, M. García-Arranz, Dolores Herreros, I. Pascual, C. Peiró, J. Rodríguez-Montes. Diseases of the Colon & Rectum, 2005

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Expanded Adipose-Derived Stem Cells for the Treatment of Complex Perianal Fistula: a Phase II Clinical Trial (2009, background): “No aberrant differentiation could be detected in biopsies taken from patients in the phase I clinical trial.(16) In view of the autologous nature of the product, discrimination between ASCderived and non-ASCYderived tissue is almost impossible.”
Characterization of freshly isolated and cultured cells derived from the fatty and fluid portions of liposuction aspirates (2006, methodology): “ASCs are currently being used in clinical trials including studies investigating bone defect (Lendeckel et al., 2004) and rectovaginal fistula (Garcia-Olmo et al., 2005) treatments and soft tissue augmentation (our unpublished data).”
Same or Not the Same? Comparison of Adipose Tissue-Derived Versus Bone Marrow-Derived Mesenchymal Stem and Stromal Cells (2012, neutral): “disease [218].”