Biotransformation of resveratrol: synthesis of trans-dehydrodimers catalyzed by laccases from Myceliophtora thermophyla and from Trametes pubescens
By Silvia Nicotra, M. Cramarossa, A. Mucci, U. Pagnoni, S. Riva, L. Forti. 2004
158 citations recorded by the source corpus.
Abstract Laccases from different sources have been used, for the first time, for the selective oxidation of the stilbenic phytoalexin trans -resveratrol (3,5,4′-trihydroxystilbene, 1a ) on a preparative scale. Specifically, the enzymes from Myceliophtora thermophyla and from Trametes pubescens gave the dehydrodimer 2a in 31 and 18% isolated yields, respectively. These results compare favorably with the reported data for the chemically catalyzed dimerization of 1a (18% yields). The antioxidant properties of 2a have also been investigated.
Subfields: Biotechnology, Geriatrics and Gerontology, Plant Science
View Paper: https://www.semanticscholar.org/paper/581afe843dfe6952b17b302d29ee35b0d438cef0
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In Biotechnology
In Plant Science
- H. Ribeiro
- A. C. E. Silva
- Márcia Jaqueline Mendonça Maciel
- Susana Rodríguez Couto
- J. L. Toca Herrera
Citations in the corpus
- Industrial and biotechnological applications of laccases: a review. (2006, background): “…in synthetic chemistry, where they have been proposed to be applicable for oxidative deprotection (Semenov et al., 1993) and production of complex polymers and medical agents (Xu, 1999 and Refs. therein, Mai et al., 2000; Uyama and Kobayashi, 2002; Kurisawa et al., 2003; Nicotra et al., 2004).”
- Industrial and biotechnological applications of ligninolytic enzymes of the basidiomycota: A review (2010, background): “…Mayer and Staples, 2002; Mikolasch et al. 2002; Stahl et al. 2002; Akta and Tanyolac, 2003; Baiocco et al. 2003; Barilli et al. 2004; Heller, 2004; Nicotra et al. 2004; Xu, 2005; Rodríguez and Toca, 2006; Kunamneni et al. 2008; Mikolasch and Schauer, 2009; Ponzoni et al. 2007 Lignin…”
- Laccases: a never-ending story (2010, background): “Laccases have been used to synthesize dyes [84] and products of pharmaceutical importance, such as the anticancer drug actinocin [85] or the phytoalexin resveratrol [86].”