BiomedCLIP: a multimodal biomedical foundation model pretrained from fifteen million scientific image-text pairs
By Sheng Zhang, Yanbo Xu, Naoto Usuyama, Hanwen Xu, J. Bagga, Robert Tinn, Sam Preston, Rajesh N. Rao, Mu-Hsin Wei, Naveen Valluri and 12 more. 2023
661 citations recorded by the source corpus.
Biomedical data is inherently multimodal, comprising physical measurements and natural language narratives. A generalist biomedical AI model needs to simultaneously process different modalities of data, including text and images. Therefore, training an effective generalist biomedical model requires high-quality multimodal data, such as parallel image-text pairs. Here, we present PMC-15M, a novel dataset that is two orders of magnitude larger than existing biomedical multimodal datasets such as MIMIC-CXR, and spans a diverse range of biomedical image types. PMC-15M contains 15 million biomedical image-text pairs collected from 4.4 million scientific articles. Based on PMC-15M, we have pretrained BiomedCLIP, a multimodal foundation model, with domain-specific adaptations tailored to biomedical vision-language processing. We conducted extensive experiments and ablation studies on standard biomedical imaging tasks from retrieval to classification to visual question-answering (VQA). BiomedCLIP achieved new state-of-the-art results in a wide range of standard datasets, substantially outperforming prior approaches. Intriguingly, by large-scale pretraining on diverse biomedical image types, BiomedCLIP even outperforms state-of-the-art radiology-specific models such as BioViL in radiology-specific tasks such as RSNA pneumonia detection. In summary, BiomedCLIP is a fully open-access foundation model that achieves state-of-the-art performance on various biomedical tasks, paving the way for transformative multimodal biomedical discovery and applications. We release our models at https://aka.ms/biomedclip to facilitate future research in multimodal biomedical AI.
Subfields: Artificial Intelligence, Computer Vision and Pattern Recognition, Radiology, Nuclear Medicine and Imaging
View Paper: https://www.semanticscholar.org/paper/5814bd146b37e13115af4330caf3a751159a156f
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Citations in the corpus
- A generalist vision–language foundation model for diverse biomedical tasks (2023, positive): “For BiomedCLIP, we added a decision layer and fine-tuned the entire model.”
- A whole-slide foundation model for digital pathology from real-world data (2024, neutral): “The improvement of our approach is larger on mutation prediction than on cancer subtyping, which may be partially attributable to richer mutation information in pathology reports from real-world data compared with text commentary in Twitter 8 and scientific papers 50 .”