Uptake through glycoprotein 2 of FimH+ bacteria by M cells initiates mucosal immune response
By K. Hase, K. Kawano, T. Nochi, G. Pontes, S. Fukuda, M. Ebisawa, K. Kadokura, T. Tobe, Yumiko Fujimura, Sayaka Kawano and 12 more. Nature, 2009
614 citations recorded by the source corpus.
Subfields: Endocrinology, Infectious Diseases, Nutrition and Dietetics
View Paper: https://www.semanticscholar.org/paper/5802022f9a456c2f725f1b5d97a72f8e03c68e26
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Citations in the corpus
- Microfold (M) cells: important immunosurveillance posts in the intestinal epithelium (2013, background): “In the absence of GP2 expression by M cells, the transcytosis of type-I-piliated bacteria was impeded.(9) Furthermore, GP2-dependent bacterial transcytosis by M cells was shown to be important for the immunosurveillance of FimHþ bacteria in the gut lumen.”
- Intestinal mucosal adherence and translocation of commensal bacteria at the early onset of type 2 diabetes: molecular mechanisms and probiotic treatment (2011, neutral): “Similarly, commensal bacteria have been proposed to translocate into the host mammary glands via MLN and Peyer’s patches in lactating mice (Hase et al, 2009; Perez et al, 2007; Sansonetti & Phalipon, 1999).”
- Pathological bacterial translocation in liver cirrhosis. (2014, background): “198 Journal of Hepatology 201 microbes [6]; lamina propria DCs compromise two different subsets: CD103CX3CR1 DCs (inducing development of regulatory T cells) and CD103 CX3CR1 DCs (with features of macrophages, promoting TNF-production and development of Th1/Th17 T cells) (2) through interaction with”
- Structure of the decoy module of human glycoprotein 2 and uromodulin and its interaction with bacterial adhesin FimH (2022, methodology): “As also detailed in the Methods, subsequent particle exclusions were performed at three different stages: (1) starting from a total of 13,616 raw micrographs, 3,767,790 helical segments were auto-picked and extracted on the basis of motion correction and CTF estimation; (2) based on 2D classificatio”