Relationship between exacerbation frequency and lung function decline in chronic obstructive pulmonary disease

By G. Donaldson, T. Seemungal, A. Bhowmik, J. Wedzicha. Thorax, 2002

2,378 citations recorded by the source corpus.

Subfields: Pulmonary and Respiratory Medicine, Sociology and Political Science

View Paper: https://www.semanticscholar.org/paper/5801e2bdc8be32fa8f9728b69557b62160c81a75

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Pulmonary and Respiratory Medicine

1. D. Parums
2. J. Wedzicha
3. P. Barnes
4. T. Seemungal
5. P. Calverley
6. A. Anzueto
7. G. Donaldson
8. Bartolome Celli

In Sociology and Political Science

1. P. Barnes
2. P. Calverley
3. J. Wedzicha
4. T. Seemungal
5. K. Rabe
6. R. Rodríguez-Roisín
7. A. Anzueto
8. Jorgen Vestbo

Citations in the corpus

• Editorial: Global Initiative for Chronic Obstructive Lung Disease (GOLD) 2023 Guidelines for COPD, Including COVID-19, Climate Change, and Air Pollution (2023, neutral): “Обострения ХОБЛ являются важными событиями в течении заболевания, так как они: • негативно влияют на качество жизни пациента [144, 391]; • ухудшают симптомы и функцию легких, причем воз" вращение к исходному уровню может занять несколь" ко недель [398]; • ускоряют темп снижения функции легких [399, ”
• Effect of pharmacotherapy on rate of decline of lung function in chronic obstructive pulmonary disease: results from the TORCH study. (2008, methodology): “There was an association between exacerbation frequency documented during the study and FEV1 decline, supporting previous observations ( 18 , 19) (Table 5). However, in patients who had no exacerbations during the study, the rate of decline TABLE 3. ADJUSTED YEARLY RATE OF DECLINE IN % PREDICTED FEV”
• American Thoracic Society/European Respiratory Society statement on pulmonary rehabilitation. (2006, background): “Exacerbations can result in a more rapid decline of lung function (213), increased peripheral muscle weakness (214), decreased quality of life (215), increased health care costs (216, 217), and increased mortality (218).”
• Long-term natural history of chronic obstructive pulmonary disease: severe exacerbations and mortality (2012, background): “Yet, recent studies report an association between exacerbations and a greater decline in lung function.(8) Moreover, increasing exacerbation frequency has been associated with higher mortality,(5) while exacerbations appear to cluster in time,(9) and a history of exacerbations is the single best pre”
• Global strategy for the diagnosis, management, and prevention of chronic obstructive pulmonary disease: GOLD executive summary. (2007, background): “d Accelerate the rate of decline of lung function (98, 99)”
• Early therapy improves outcomes of exacerbations of chronic obstructive pulmonary disease. (2004, background): “The frequency of exacerbations has been shown to be an important determinant of the impaired health-related quality of life seen in COPD (2) and to affect decline in lung function ( 3 , 4). Exacerbations are a frequent cause of physician consultation in primary and secondary care and a major cause o”
• Infections and airway inflammation in chronic obstructive pulmonary disease severe exacerbations. (2006, background): “org acute morbidity, mortality, and cost, exacerbations are also associated with major reductions in long-term quality of life and lung function (3, 4).”