Runx2 Is a Common Target of Transforming Growth Factor β1 and Bone Morphogenetic Protein 2, and Cooperation between Runx2 and Smad5 Induces Osteoblast-Specific Gene Expression in the Pluripotent…

By Kyeong‐Sook Lee, Hyun-Jung Kim, Qing-lin Li, X. Chi, C. Ueta, T. Komori, J. Wozney, Eung-Gook Kim, Je‐Young Choi, H. Ryoo and 1 more. Molecular and Cellular Biology, 2000

902 citations recorded by the source corpus.

Subfields: Molecular Biology, Oncology

View Paper: https://www.semanticscholar.org/paper/5702fd05451d6ce11867b416604e9a3dfe61824e

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In Molecular Biology

1. R. Baron
2. T. Komori

Citations in the corpus

• BMP‐2 Controls Alkaline Phosphatase Expression and Osteoblast Mineralization by a Wnt Autocrine Loop (2003, background): “In the case of C2C12 cells, Lee et al.((48)) found a slight increase in ALP activity in cells overexpressing Runx2, whereas Zhang et al.”
• Regulation of bone development and extracellular matrix protein genes by RUNX2 (2009, background): “…of the in vivo studies, in vitro studies have demonstrated that RUNX2 is a positive regulator that can upregulate the expression of bone matrix protein genes including Col1a1, Spp1, Ibsp, Bglap, and Fn1 (fibronectin 1) (Ducy et al. 1997; Sato et al. 1998; Harada et al. 1999; Lee et al. 2000).”