Association of Polymerase e-Mutated and Microsatellite-Instable Endometrial Cancers With Neoantigen Load, Number of Tumor-Infiltrating Lymphocytes, and Expression of PD-1 and PD-L1.

By B. Howitt, S. Shukla, L. Sholl, Lauren L. Ritterhouse, J. Watkins, S. Rodig, E. Stover, K. Strickland, A. D’Andrea, Catherine J. Wu and 2 more. JAMA Oncology, 2015

630 citations recorded by the source corpus.

Subfields: Immunology, Obstetrics and Gynecology, Oncology

View Paper: https://www.semanticscholar.org/paper/56e4f81ac634fea98482d9a7b6878eae8718e0e9

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Citations in the corpus

• Efficacy of Pembrolizumab in Patients With Noncolorectal High Microsatellite Instability/Mismatch Repair-Deficient Cancer: Results From the Phase II KEYNOTE-158 Study. (2020, background): “Cells from mismatch repair–deficient tumors can express programmed death ligand 1 (PD-L1) on their membrane.(11) Furthermore, these tumors have microscopic evidence of high numbers of infiltrating lymphocytes, and it is common for these immune cells to display upregulated checkpoint proteins, includ”