BMP receptor signaling: transcriptional targets, regulation of signals, and signaling cross-talk.

By K. Miyazono, S. Maeda, T. Imamura. Cytokine & growth factor reviews, 2005

924 citations recorded by the source corpus.

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

Cellular and Molecular Basis of Pulmonary Arterial Hypertension (2009, background): “BMPs are now known to regulate growth, differentiation, and apoptosis in a diverse number of cell lines (77).”
Bone substitutes in orthopaedic surgery: from basic science to clinical practice (2014, background): “Originally identified and named after their ability to induce ectopic bone formation [103], bone morphogenetic proteins (BMPs) represent a wide and heterogeneous family of highly conserved secreted proteins, within the transforming growth factor-b superfamily, deeply involved in the skeletogenic pro”
Modern pathogenetic concepts of liver fibrosis suggest stellate cells and TGF-β as major players and therapeutic targets (2006, background): “Interestingly, in vitro and in vivo evidence suggests a promoting role for TGF-β in EMT but bone morphogenetic protein (BMP), another member of the TGF-β super-family [38], counteracts this process.”
Building muscle: molecular regulation of myogenesis. (2012, background): “BMPs exert their activities through serine-threonine kinase receptors leading to activation of SMAD proteins and subsequent activation, or repression, of target genes (Liu et al. 1995; Miyazono et al. 2005).”