Mouse Genome Database (MGD)-2018: knowledgebase for the laboratory mouse

By Cynthia L. Smith, Judith A. Blake, J. Kadin, J. Richardson, Carol J. Bult, The Mouse Genome Database Group. 2017

228 citations recorded by the source corpus.

Abstract The Mouse Genome Database (MGD; http://www.informatics.jax.org) is the key community mouse database which supports basic, translational and computational research by providing integrated data on the genetics, genomics, and biology of the laboratory mouse. MGD serves as the source for biological reference data sets related to mouse genes, gene functions, phenotypes and disease models with an increasing emphasis on the association of these data to human biology and disease. We report here on recent enhancements to this resource, including improved access to mouse disease model and human phenotype data and enhanced relationships of mouse models to human disease.

Subfields: Molecular Biology

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In Molecular Biology

1. Gene Ontology Consortium
2. Andrea Pierleoni
3. Miguel Pignatelli

Citations in the corpus

• The Gene Ontology Resource: 20 years and still GOing strong (2018, methodology): “The GO ribbon visualization metaphor borrows from a viewer originally developed by the Mouse Genome Database team (28), but in contrast, the GO ribbon was developed as a lightweight, reusable widget that can be embedded in any website, and retrieves data directly from the GO resource via API.”
• Open Targets Platform: new developments and updates two years on (2018, methodology): “We list the annotated strain-specific phenotypes and the allelic composition of every laboratory mouse with a knockout gene curated by and available in the Mouse Genome Informatics database (23).”