Obstructive sleep apnea as a risk factor for stroke and death.

By H. Yaggi, J. Concato, W. Kernan, J. Lichtman, L. Brass, V. Mohsenin. New England Journal of Medicine, 2005

3,073 citations recorded by the source corpus.

Subfields: Physiology, Pulmonary and Respiratory Medicine

View Paper: https://www.semanticscholar.org/paper/562d03e9d7db4138cd43b3de02dd94de8a6ab7b1

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In Physiology

In Pulmonary and Respiratory Medicine

Citations in the corpus

Factors Influencing the Decline in Stroke Mortality (2013, background): “stroke and for the combined end point of stroke and death in prospective studies.(382,383) In the Sleep Heart Health Study,”
Sleep-Disordered Breathing and Mortality: A Prospective Cohort Study (2009, background): “Evidence from clinic-based studies suggests that patients with sleep-disordered breathing have a higher mortality risk and that treatment with positive airway pressure during sleep may attenuate this risk [3– 19].”
Sleep Disorders and Sleep Deprivation: An Unmet Public Health Problem (2006, background): “However, an observational cohort study of 1,022 individuals, where 68 percent of individuals had OSA (apnea-hypopnea index of 5 or higher), showed that OSA syndrome significantly increased the risk of stroke or death from any cause, and the increase is independent of other risk factors, including hy”
Sleep apnea and cardiovascular disease: an American Heart Association/American College of Cardiology Foundation Scientific Statement from the American Heart Association Council for High Blood Pressure Research Professional Education Committee, Council on Clinical Cardiology, Stroke Council, and Coun (2008, background): “In an analysis of the effects of OSA on the composite outcome of stroke or death (213), another study reported that increasing severity of sleep apnea was associated with an increased risk of stroke or death independently of age, sex, race, smoking, alcohol, BMI, diabetes, hyperlipidemia, atrial fib”
Increased prevalence of sleep-disordered breathing in adults. (2013, background): “The estimated increases translate to millions of additional afflicted persons in the United States, and, consequently, incidences of sequelae of SDB, such as cardiovascular morbidities and stroke (1, 33, 34), cognitive decline (4), depression (7), and premature death (8, 9), are likely accelerated r”
Obstructive sleep apnea is a common disorder in the population-a review on the epidemiology of sleep apnea. (2015, background): “followed 1,022 patients being investigated on clinical grounds an concluded that OSA syndrome significantly increases the risk of stroke or death from any cause, and the increase is independent of other risk factors, including hypertension (89) .”
Defining phenotypic causes of obstructive sleep apnea. Identification of novel therapeutic targets. (2013, methodology): “(2) When CPAP is dropped, the upper airway narrows and limits ventilation.”
The epidemiology of adult obstructive sleep apnea. (2008, background): “There is now a wealth of information indicating that untreated obstructive sleep apnea is associated with an increased risk of fatal and nonfatal cardiovascular event (4), a higher propensity of sudden death during sleep (98), and a greater risk for stroke and all-cause mortality (99).”