Early Tagging of Cortical Networks Is Required for the Formation of Enduring Associative Memory

By Edith Lesburguères, O. Gobbo, S. Alaux-Cantin, Anne Hambucken, P. Trifilieff, B. Bontempi. 2011

337 citations recorded by the source corpus.

Subfields: Cellular and Molecular Neuroscience, Cognitive Neuroscience, Neurology

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Citations in the corpus

Replay in Deep Learning: Current Approaches and Missing Biological Elements (2021, neutral): “…are created, neurons are allocated in both the hippocampus and medial prefrontal cortex, with unused neurons in the hippocampus engaged immediately for formation and neurons in medial prefrontal cortex being epigenetically tagged for later storage (Lesburguères et al., 2011; Bero et al., 2014).”
Cellular and Systems Consolidation of Declarative Memory (2017, background): “Lesburguères et al (2011) presented initial evidence for an AMPA-and NMDA receptor dependent " tagging process " in the cortex during encoding, which was crucial for the progressive hippocampaldriven rewiring of cortical networks supporting remote memory storage.”
Memory consolidation. (2015, background): “The concept of rapid cortical tagging (Lesburgueres et al. 2011; Tse et al. 2011) suggests that, even if the hippocampus is normally engaged for a short period for “binding” disparate cortical networks during memory encoding and the early stages of consolidation, a memory trace of some kind is rapid”
The restless engram: consolidations never end. (2012, result): “These findings are in agreement with the assertion of earlier models that initial memory is in both the HPC and the neocortex (see also Lesburgueres et al. 2011), but they are in disagreement with the assumption that the neocortex is a slow learner (on additional evidence for fast cortical…”
The hippocampus and related neocortical structures in memory transformation. (2018, background): “The importance of mPFC-hippocampal interactions shortly after learning to support the formation of short-term and remote memories is highlighted in studies on socially acquired food preferences by Lesburguères et al. [142].”
Loss of Ensemble Segregation in Dentate Gyrus, but not in Somatosensory Cortex, during Contextual Fear Memory Generalization (2016, background): “Early tagging of cortical networks upon encoding has been shown to be necessary for enduring memory formation (Lesburguères et al., 2011), and optogenetic reactivation of the cortical ensemble engaged by contextual fear conditioning has been shown to be sufficient for the retrieval of memory (Cowans”
Early remodeling of the neocortex upon episodic memory encoding (2014, result): “As previous data indicate that late-stage memory consolidation requires hippocampus-driven reorganization of neocortical circuits (5, 16), our data support a stage-dependent directionality model of memory-relevant information flow, in which neocortex-driven hippocampal activity is critical for memor”