Altered brain microRNA biogenesis contributes to phenotypic deficits in a 22q11-deletion mouse model

By K. Stark, Bin Xu, A. Bagchi, W. Lai, Hui Liu, Ruby Hsu, Xiang Wan, Paul Pavlidis, A. Mills, M. Karayiorgou and 1 more. Nature Genetics, 2008

609 citations recorded by the source corpus.

Subfields: Cancer Research, Genetics, Molecular Biology

View Paper: https://www.semanticscholar.org/paper/55e89b5753e4fb6e53c7b9b796bccfe0ec1d2480

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Cancer Research

1. Danish H Sayed
2. M. Abdellatif

In Molecular Biology

1. Danish H Sayed
2. Bin Xu
3. M. Abdellatif

Citations in the corpus

• Dendritic spine pathology in neuropsychiatric disorders (2011, background): “2 microdeletion syndrome is the most common CNV associated with schizophrenia, accounting for 1–2% of case”
• MicroRNAs in development and disease. (2011, background): “(579) generated a mouse model with an equivalent deletion that spans a 1.”
• Strong association of de novo copy number mutations with sporadic schizophrenia (2008, background): “2 microdeletion removes one copy of another key gene in this pathway, DGCR8 /( PASHA ), and the resulting abnormality in miRNA biogenesis contributes to the behavioral and neuronal deficits associated with this CN mutation in a mouse mode”